| abstract |
The present invention provides the PDE9 inhibitor represented by formula (I), which is effective for overactive bladder, frequent urination, urinary incontinence, dysuria associated with benign prostatic hypertrophy, urinary tract stones, Alzheimer's disease, chronic obstructive pulmonary disease, A thienopyrimidine derivative or a salt thereof useful for the prevention or treatment of myocardial infarction, thrombosis, diabetes, etc., In formula (I), R 1 represents a hydrogen atom, an alkyl group, etc.; R 2 represents a hydrogen atom, an alkyl group, an amino group, etc.; R 3 represents an alkyl group, an alkenyl group, an alkylthio group or a YX group, or, R 2 Together with R 3 , tetramethylene can be formed; X represents a direct bond or a linking group such as CH 2 , CH(OH), S, O, NH; Z represents S or O; n represents an integer from 1 to 4. |