http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101168555-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fbb5066c7e1941f1fc2afaedab22711 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 2006-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2756cc15d34ecd5f6194073cc2cb356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6d20230d3c59b36b2a1b06086c6de39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94ce9e4cde22b6c25a36eb6c9d463240 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a92ae175e89e8b2148d2b1976691bbfb |
| publicationDate | 2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101168555-B |
| titleOfInvention | A kind of preparation of medicine and derivative thereof |
| abstract | The invention relates to a preparation method of a medicine and its derivatives, in particular to the preparation of the medicine and its derivatives (VI) by using compound (I) as a starting material. Compound (I) is a class of very useful intermediates. The desired drug and its derivatives can be obtained through a shorter route. The reaction steps are common in the synthesis of steroids. The reactions involved mainly include Grignard, 21 Hydrolysis at position 21, esterification at position 21, replacement of iodine at position 21. Compared with the existing methods, the route is simple, easy to industrialize and low in cost. In particular, the compound of formula (VIII) in compound (I) is a completely new structure compound. Compound (I) Difluorocorone derivative (VI) |
| priorityDate | 2006-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.