| abstract |
The invention discloses nifedipine controlled release medicament, which contains a pastille layer and a boosting layer with the proportion of 1: 0.5-3 by weight, wherein the pastille layer contains nifedipine and carrying agent which is the homopolymer of vinylpyrrohdone and /or copolymer of vinylpyrrohdone and is 40-99% of the pastille layer, the boosting layer includes infiltration promoting polymer which is 10-80% of the boosting layer by weight, insoluble polymer which is 10-80% of the boosting layer by weight, and the other component is osmotic pressure accelerant The rate of medicament releasing controlled by nifedipine can make the medicament release the nifedipine in 24 hours by administering drug once a day. |