| abstract |
A compound represented by the general formula below or a salt thereof is a useful intermediate in the production of a [2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine compound that has excellent cell adhesion inhibitory effect and cell invasion inhibitory effect and therefore is useful as a therapeutic or prophylactic agent for various inflammatory diseases and autoimmune diseases induced by the adhesion and invasion of leukocytes, such as inflammatory bowel diseases (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. [Chemical formulae] wherein R<SUP>1</SUP> and R<SUP>2</SUP> independently represent a hydrogen atom or an amino-protecting group for an amino group, or R<SUP>1</SUP> and R<SUP>2</SUP> may together form a pyrrole ring which may have a substituent. |