http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101146531-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b70512b2076a2759fccaecf9fe962d5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5685 |
| filingDate | 2006-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d27d1945ae5e0ea91e5e1edcee61ef2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28d92b848e1f5914c858e28008cb810 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35d570ef973f5d734fc2c37e58f09286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d8cd62750a10592ee0fe1fceac71fc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb0fad4b214604adc467f42a5f1bf2e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37274f2a9f3bc262e265cd885110e66 |
| publicationDate | 2008-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101146531-A |
| titleOfInvention | Pharmaceutical compounds |
| abstract | The invention provides a combination of an ancillary agent and a compound having the formula (0): or salts or tautomers or N-oxides or solvates thereof; wherein the ancillary agent is selected from: a monoclonal antibody, an alkylating agent, an anticancer agent, a further CDK inhibitor and a hormone, hormone agonist, hormone antagonist or hormone modulating agent; X is a group R<1>-A-NR<4>- or a 5- or 6-membered carbocyclic or heterocyclic ring; A is a bond, SO2, C=O, NR<9>(C=O) or 0(C=O) wherein R<9> is hydrogen or C1-4hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy; Y is a bond or an alkylene chain of 1 , 2 or 3 carbon atoms in length; R<1> is hydrogen; a carbocyclic or heterocyclic group having from 3 to 12 ring members; or a C1-8 hydrocarbyl group optionally substituted by one or more substituents selected from halogen (e.g. fluorine), hydroxy, C1-4 hydrocarbyloxy, amino, mono- or di-C1-4 hydrocarbylamino, and carbocyclic or heterocyclic groups having from 3 to 12 ring members, and wherein 1 or 2 of the carbon atoms of the hydrocarbyl group may optionally be replaced by an atom or group selected from O, S, NH, SO, SO2; R<2> is hydrogen; halogen; C1-4alkoxy (e.g. methoxy); or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy); R<3 >is selected from hydrogen and carbocyclic and heterocyclic groups having from 3 to 12 ring members; and R<4> is hydrogen or a C1-4hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102060772-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110724106-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110724106-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111116374-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111116374-B |
| priorityDate | 2005-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1869.