| abstract |
The field of the invention particularly includes oral drugs or the pharmaceutical composition of the type of one or more active component.It is an object of the invention to provide the oral drugs of a kind of improvement, it is with once a day or several times dosed administration, and can improve release of active ingredients (particularly a kind of active component), thus improves prevention and the therapeutic effect of described medicine.Achieving this purpose by the multiparticulates pharmaceutical dosage forms of the present invention, wherein the release of active component is controlled by double release trigger mechanisms: " time dependence release " and " pH dependent release ".Described medicine includes providing the microcapsule improving release of active ingredients, and each microcapsule includes the core comprising active component and one or more swellers and at least one is for improving the coating of release of active ingredients. |