abstract |
The invention provides composition and method, in mammalian cell (comprising people's cell), suppress the cell cycle G2 outpost of the tax office, specifically the G2 outpost of the tax office that causes of dna damage.Specifically, the invention provides composition and method, make cell to dna damage agent sensitivity by eliminating the cell cycle G2 outpost of the tax office.The compounds of this invention is used for the treatment of for example cancer of proliferative disease.The invention provides composition and method, selectivity makes the impaired cancer cell in the G1 outpost of the tax office responsive to dna damage agent and treatment. |