| abstract |
The related new synthesis technique for Sunpla or Eptaplatin comprises: preparing the complex of M2{Pt[CH2(COO)2]2} with M2PtCl4 and CH2(COOM)2; then reacting with the carrier group of amine(4R, 5R)-4, 5-bi(aminomethyl)-2-isopropyl-1, 3-cyclopentane dioxide. This invention has high yield with short synthesis path and no harmful Ag and Hg to provide high-pure bulk drug. |