http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100462362-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d0e4f1f9b0db0e0b8aa3bef746062c9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D337-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-14 |
| filingDate | 2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfdb7c32f14a08e621bcf24d7989f5af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f304c7cbb7318693084b2d6d95659268 |
| publicationDate | 2009-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-100462362-C |
| titleOfInvention | Preparing process of 2-(10-oxy-10,11-dihydrodibenz [b,f]-thiotropilium-2-yl) propionic acid |
| abstract | The improved preparation process of zaltoprofen, named chemically as 2-(10-oxy-10, 11-dihydrodibenz [b, f]-thiotrppilium-2-yl) propionic acid, includes the following steps: rearrangement reaction of 5-propionyl-2-thiophenyl phenylacetate, iodine and triamyl orthoformate in the presence or absence of catalyst to obtain 5-(1-alkoxycarbonylethyl)-2-thiophenyl phenylacetate; hydrolyzing the said reaction product in water solution of alkali metal hydroxide and acidifying to obtain 5-(1-carboxylethyl)-2-thiophenyl phenylacetate; and the cyclization of 5-(1-carboxylethyl)-2-thiophenyl phenylacetate in the presence of polyphosphate to obtain the ultimate product. The present invention has low cost, less reaction steps, high yield, simple operation and no environmental pollution. |
| priorityDate | 2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.