http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CL-2022001190-A1

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filingDate 2022-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa6cfb6b91f1fd26bf359dccb8b7dbee
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publicationDate 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CL-2022001190-A1
titleOfInvention Combination therapy with 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
abstract Provided herein are methods for treating, preventing, controlling and/or ameliorating hypotension related to the administration of 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1 -oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, cocrystal, clathrate or polymorph thereof in a patient with cancer, wherein the methods comprise administering a combination comprising 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2 -difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, cocrystal, clathrate or polymorph thereof and a glucocorticoid receptor agonist, interleukin-1 receptor antagonist or blocker of interleukin 1ß
priorityDate 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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