abstract |
Provided herein are methods for treating, preventing, controlling and/or ameliorating hypotension related to the administration of 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1 -oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, cocrystal, clathrate or polymorph thereof in a patient with cancer, wherein the methods comprise administering a combination comprising 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2 -difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, cocrystal, clathrate or polymorph thereof and a glucocorticoid receptor agonist, interleukin-1 receptor antagonist or blocker of interleukin 1ß |