| abstract |
The present invention relates to salts and crystalline forms of 2– (3– (8-amino-6– (trifluoromethyl) imidazo [1,2-a] pyrazin-3-yl) -4-methylphenyl) -3,3, 3 – trifluoro – 2– hydroxypropanamide, crystalline forms of 8 – amino – N– (2 – hydroxy – 2 – methylpropyl) –3– (2– methyl – 5– (1,1,1 – trifluoro – 2 – hydroxypropan – 2 –Il) phenyl) imidazo [1,2-a] pyrazine-6-carboxamide and crystalline forms of 8-amino-N– (2-hydroxy-2-methylpropyl) -3– (2– (methyl-d3) –5 - (1,1,1– trifluoro-2-hydroxypropan-2-yl) phenyl) imidazo [1,2-a] pyrazine-6-carboxamide, which are PI3K inhibitors useful in the treatment of cancer and other diseases. |