| abstract |
THE PRESENT INVENTION REFERS TO CONJUGATES THAT INCLUDE A CHELANT REMAINDER OF A METALLIC COMPLEX OF THE SAME AND A THERAPEUTIC OR DIRECTED REMAINDER, METHODS FOR THEIR PRODUCTION AND USES OF THE SAME. THE PRESENT INVENTION IS ADDRESSED TO MONOCLONAL ANTIBODIES THAT TARGET THE RECEIVER OF GROWTH FACTOR 1 SIMILAR TO INSULIN AND TO THE RADIOIMMUNOCONJUGATES OF THE SAME THAT DEMONSTRATE A GREATER POWER AND IMPROVE THE EXCRETION OF A MISCELLANEOUS METAL COMPLEX, WHICH IS A MISCELLANEOUS COMPLEX MATCHES WITH A THERAPEUTIC REST, A DIRECTED FRACTION, OR A RETICULATION GROUP. IN ANOTHER ASPECT, THE INVENTION PRESENTS A PHARMACEUTICAL COMPOSITION INCLUDING A COMPOUND OF THE INVENTION; AND A PHARMACEUTICALLY ACCEPTABLE EXCIPIENT. IN ANOTHER ASPECT, THE INVENTION PRESENTS A METHOD OF PLANNING THE RADIATION TREATMENT AND / OR RADIATION TREATMENT, THE METHOD INCLUDES ADMINISTERING A SUBJECT IN NEED OF A COMPOUND OR PHARMACEUTICAL COMPOSITION OF THE INVENTION. |