| abstract |
A PHARMACEUTICAL COMPOSITION INCLUDING I) A BISPECIFIC ANTIBODY CONSTRUCTION, WHICH IS JOINED TO A TARGET CELLULAR SURFACE ANTIGEN THROUGH A FIRST BINDING DOMAIN AND TO THE SURFACE ANTIGEN OF A LYMPHOCYTES DOMAIN OF A CD3 T-DOMAIN THE CHAIN ANTIBODY CONSTRUCTION IS PRESENT IN A CONCENTRATION IN THE RANGE OF 0.5 µG / ML TO 20 MG / ML, PREFERENTIALLY FROM 0.5 µG / ML TO 10 OR 5 MG / ML; II) AT LEAST ONE PRESERVATIVE SELECTED FROM BENZYL ALCOHOL, CHLOROBUTANOL, META-CRESOL, METHYLPARABENE, PHENOXYETHANOL, PROPYLPARABENE AND TIOMEROSAL AT A CONCENTRATION EFFECTIVE TO INHIBIT THE GROWTH OF ESTABLISHED MICROBIALS, ESSENTIAL BUILDING, AND III) ESTIMATE BUILDING. |