abstract |
<p> A composition for preventing or treating hyperlipidemia, fatty liver or atherosclerosis comprising an oxintomodulin derivative as an active ingredient. The oxintomodulin derivative has a great ability to activate the G1-P-1 receptor and glucagon receptor compared to native oxintomodulin and has the effects of reducing blood cholesterol, low density cholesterol and triglyceride levels They rise by high fat diets and increase high density cholesterol levels and the relationship between high and low density cholesterol. Therefore, the oxintomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases, </p> |