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filingDate 2014-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62cb94dc5a4f2638d49a566f4d37de8b
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publicationDate 2015-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CL-2014002062-A1
titleOfInvention Composed of small molecules that inhibit cdk8 and cdk19, excluding cortistatin a and others; farm formulation; a method to treat a mammal that has a disease related to cdk1 like e. Alzheimer's, other dementias, amyloidosis, and a method to chemoprotect a patient suffering from ovarian or breast cancer, among others.
abstract The invention relates to the compounds and methods for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds and methods for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI -related diseases. The invention provides new compounds having improved solubility and / or potency, and methods for their use. In various aspects, the invention relates to the treatment of cancer. The invention provides meth
priorityDate 2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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