| titleOfInvention |
Compounds derived from (hetero) aryl-substituted cyclohexane, pharmaceutical composition containing said compound and its use as modulators of the ยต-opioid receptor and the orl-1 receptor to treat pain, anxiety, depression, epilepsy, Alzheimer's, senile dementia, withdrawal symptoms, alcohol abuse. |
| abstract |
COMPOUNDS OF GENERAL FORMULA 1, WHERE R1, R2, R3, Y1, Y1 ', Y2, Y2', Y3, Y3 ', Y4, Y4', AND Q ARE AS DEFINED IN THE SPECIFICATIONS OF CLAIMS THAT HAVE AFFINITY WITH THE RECEIVER OF OPLOIDES IJ AND WITH THE RECEIVER ORL-1; PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS IN THE FORM OF AN INDIVIDUAL STEREOISOMER OR A MIXTURE OF SEVERAL OF THE FREE COMPOUNDS AND / OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS AND / OR SOLVATES; AND ITS USE TO TREAT PAIN, ANXIETY, DEPRESSION, EPILEPSY, ALZHEIMER, SENILE DEMENTIA, WITHDRAWAL SYMPTOMS, ALCOHOL ABUSE .. |