http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CL-2008002316-A1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
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filingDate 2008-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_134d0302d0b7f4e1efb98f7b5632c393
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publicationDate 2009-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CL-2008002316-A1
titleOfInvention Nitrogen heterocyclic compounds containing substituted phenylenediamine, inhibitors of the interaction between mdm2 and p53; preparation procedure; pharmaceutical composition; pharmaceutical combination; and use in the treatment of cancer.
abstract A COMPOUND OF FORMULA (I), A FORM OF N-OXIDE, AN ADDITION SALT, A STEREOCHEMICALLY ISOMERIC FORM OR A SOLVATE OF THE SAME, OR ITS POLYMORPHIC FORM. USE OF SAID COMPOUND IN THE PREPARATION OF A USEFUL MEDICINE FOR THE TREATMENT OF A DISORDER MEDIATED BY AN INTERACTION BETWEEN P53-MDM2. <br /> A PHARMACEUTICAL COMPOSITION THAT INCLUDES ACCEPTABLE CARRIERS FOR PHARMACEUTICAL USE AND AS AN EFFECTIVE AMOUNT OF ACTIVE INGREDIENT SAID COMPOUND. A PHARMACEUTICAL COMBINATION THAT INCLUDES ONE OR MORE ANTI-CANCER AGENTS AND SAID COMPOUND. A PROCESS FOR PREPARING SUCH PHARMACEUTICAL COMPOSITION IN WHICH THE CARRIERS ACCEPTABLE FOR PHARMACEUTICAL USE AND SUCH COMPOUND ARE INTIMELY MIXED. <br />
priorityDate 2007-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
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Total number of triples: 21.