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filingDate 2008-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CL-2008001497-A1
titleOfInvention Prokaryotic phenylalanine (pal) ammonia lyase variant with substitutions at the cysteines at positions 503 and / or 565 by serine; pharmaceutical composition comprising it; and its use to treat a disease caused in whole or in part by a deficiency of phenylalanine hydroxylase (pah) such as phenylketonuria.
abstract VARIANT OF LIASA AMMONIACAL OF PHENYLALANINE (PAL) PROCARIOTA WITH SUBSTITUTIONS IN THE CYSTEINS OF POSITIONS 503 AND / OR 565 BY SERINE; <br /> PHARMACEUTICAL COMPOSITION THAT INCLUDES IT; AND ITS USE TO TREAT A DISEASE CAUSED IN WHOLE OR IN PART BY A DEFICIENCY <br /> OF PHENYLALANINE HYDROXYLASE (PAH) SUCH AS PHENYLKETHANURIA. <br />
priorityDate 2007-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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