| titleOfInvention |
Isoquinoline and isoquinolinone derived compounds, rho-kinase inhibitors; pharmaceutical composition; and use to treat and / or prevent hypertension, retinopathy, glaucoma, pulmonary fibrosis, Alzheimer's, erectile dysfunction, thrombotic disorders, among others. |
| abstract |
COMPOSED OF FORMULA (I), WHERE R1-R8, N, MYL ARE AS DEFINED IN THE CLAIMS, OR ITS STEREOISOMERIC AND / OR TAUTOMERIC FORMS AND / OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS. <br /> USE OF SUCH A COMPOUND. <br /> ITS PHARMACEUTICALLY ACCEPTABLE SALTS TO TREAT AND / OR PREVENT HYPERTENSION, RETINOPATHY, GLAUCOMA, PULMONARY FIBROSIS, ALZHEIMER, ERECTILE DYSFUNCTION, THROMBOTIC DISORDERS, AMONG OTHERS. PHARMACEUTICAL COMPOSITION INCLUDING A QUANTITY OF SAID COMPOUND AND / OR A SALT <br /> PHARMACEUTICALLY ACCEPTABLE OF SAME, EXCIPIENTS AND PHYSIOLOGICALLY TOLERATED VEHICLES AND, WHERE APPROPRIATE, ADDITIVES. <br /> |