| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_082c64195d690777d20391e0e8a39ed0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0634 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2019-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_becfeaa1f09348f572ec170d4c13d7c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d5e83105b74abbae5c8e8801638575c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8de59d0cfb03ddc1f7e2b838df5d73b1 |
| publicationDate |
2021-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CH-716483-A2 |
| titleOfInvention |
Process for the preparation of a therapeutic agent containing exosomes. |
| abstract |
Disclosed herein is a method of making an exosome-containing therapeutic agent comprising the steps of: separating mononuclear cells from a bone marrow sample from a healthy donor; Treating the separated mononuclear cells in a culture medium at 37 ° C. and at 5% CO 2 for 48-72 h; Separating an exosome composition from the culture medium; Dissolving the separated exosome composition in a phosphate buffer to obtain therapeutic agents containing the exosome. The culture medium comprises a 1: 1 mixture of DMEM / F12 and HEPES, 2 mmol / ml or 3.65 mg / 10 ml L-glutamine, 100 units / ml penicillin, 100 µg / ml streptomycin, 10% fetal bovine serum. |
| priorityDate |
2019-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |