http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-697394-B1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_669b0dc0ff65a0d7f1fdc0a205183de7
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01F17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B51-00
filingDate 2005-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b69370b3821c13c96d95e48d276ce5ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d87a0a160e83edc23c7983bd95babf58
publicationDate 2008-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-697394-B1
titleOfInvention Process for producing synthetic taxanes.
abstract The present invention relates to a process for the preparation of synthetic taxanes in which the 7-OH group is protected with lanthanide compounds. Its advantages are a simple process and a firm and reliable bond. Furthermore, in the subsequent process in the 7-position, no acylate is formed, and the hydrolysis of the 2'-ester groups in the acylated products becomes easily controllable. In the processes for producing synthetic taxanes, tetrahydrafuran is used as the acylating medium in the present invention, which not only achieves the same effects as pyridine, but also avoids the odor, thereby solving the problem of extremely high demands on the production facility. The present invention can be used not only for the production of semisynthetic taxanes using natural taxanes as raw material but also for the production of fully synthetic taxanes.
priorityDate 2004-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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