| abstract |
Compounds of formula I <IMAGE> wherein A is a radical of formula (???1) or (???1> <IMAGE> wherein R is C1-11 alkylene or C2-11 alkenylene Z is -OH, NR4R5, -NR4R5R6, -NHOH, or guanidino or ureido, R1 is C1-5 alkylene R2 is hydrogen, -CO-NH2, <IMAGE> or a sugar residue R3 is hydrogen or a sugar residue, R4 is hydrogen, C1-3 alkyl or a sugar residue R5 is hydrogen or C1-3 alkyl, and R6 is C1-3 alkyl and >N-CH(Z1)-CO-, A', Y1, Y2, B, C, D, E and F have the meanings recited in Claim 1 in free form, salt form or complex form, have pharmacological activity, in particular GH-, gastric and pancreatic secretion inhibiting activity. |