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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54
filingDate 1987-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ee4820dc0b5210bf3351aa4fc3dcbf
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publicationDate 1989-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-672314-A5
titleOfInvention Cimetidine reformer A prepn.
abstract Prepn. of the A modification of cimetidine (I-A; N-cyano-N' methyl-N'-(2-((5-methylimidazol- 4-yl)methylthio)ethyl) guanidine) from the H-modification (I-H; also called cimetidine M-1) comprises thermal dehdyration with a flow of gas preheated to 40-110 deg.C. The gas (which may be air, inert gas or N2) is at 60-100 deg.C and dehydration is carried out while maintaining the crystalline state at all times.
priorityDate 1986-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 23.