http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-667270-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1985-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efd68d7c5352b725f127ea682267db82 |
| publicationDate | 1988-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-667270-A5 |
| titleOfInvention | New diazepino-indole derivs. - useful as antidepressant, anti-aggressive, anxiolytic and neuroleptic agents |
| abstract | 2,3,4,5-Tetrahydro-11-phenyl 1H-(1,4)-diazepino(1,7-a) indoles (I) and their acid-addn. salts are new. (I) are pref. of formula (Ia); where R1 and R2=H, F, Cl, Br, 1-4C alkyl, 1-4C alkoxy or CF3; R3=H, 1-4C alkyl, 3-6C cycloalkyl, (3-6C) cycloalkyl (1-3C) alkyl, 3-5C alkenyl or 3-5C alkynyl; and R4-R6=H or 1-4C alkyl. 3-Cyclopropylmethl- 2,3,4,5- tetrahydro-11 -phenyl-1H-(1,4)-diazepino (1,7-a) indole is specifically claimed. A prepn. is also claimed. USE - (I) are esp. useful as antidepressants at daily doses of 25-500 mg. They are also useful as antiaggressive and anxiolytic agents at 20-300 mg/day and as neuroleptics (e.g. antischizophrenic agents) at 25-600 mg/day. |
| priorityDate | 1985-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.