http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-667091-A5
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-82 |
filingDate | 1986-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02bbd8568c2c2e9378cca53a1f96ede http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ecbc34415783a924d94cfd7d52a6ea9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04be0aaef552e96923a25ac6ce16abe3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d42bf8ee08b104dacc46bc2c1de6aa |
publicationDate | 1988-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-667091-A5 |
titleOfInvention | N-Substd. 2-imino-benzothiazoline prodn. - from the unsubstd. deriv. and amine in presence of acidic catalyst |
abstract | Prodn. of N-substd. 2-iminobenzothiazolines of formula (I) is effected by reacting 2-iminobenzothiazoline of formula (II) with an amine of formula R2NH2 (III) in the presence of an acid catalyst. In formulae, R1=alkyl, R2=opt. substd. alkyl or benzyl; and Rn= H, alkyl gps., halogen atoms, NO2, alkoxy or alkanoyl gps. or a CN gp. The reaction is effected at 100-200 deg.C in an inert organic solvent in the presence of 5-50 mole.% p-toluenesulphonic acid (TsOH). The (III):(II) molar ratio is 10-30:1. USE/ADVANTAGE - (I) are useful as intermediates, e.g. for pharmaceuticals. The process is simple and gives high yields (e.g. 91-99%) of high purity (I). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2649702-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5068238-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0408437-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0408437-A3 |
priorityDate | 1986-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.