http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-665558-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f353af12db08b6b7836ed3789d83b8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1694 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 |
| filingDate | 1985-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b084f5cad92a578583c9ecde6d12b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973a1e0ecc30b962d94d9e829cc3164a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e4ce01e9d7577c34ab070d95c91d12 |
| publicationDate | 1988-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-665558-A5 |
| titleOfInvention | Phase sepn. prodn. of microcapsules for water soluble pharmaceuticals - using fluoro-substd. aliphatic hydrocarbon as non-solvent in the hardening stage |
| abstract | In the phase-sepn. process for microencapsulation of water-soluble pharmaceuticals, the new feature is that the capsules are hardened at 0-25 deg.C, and that during this stage at least one fluoro- or fluorohalo-aliphatic hydrocarbon (A) is used as non-solvent. An excess of (A), relative to the total vol. of solvent and non-solvent originating from the phase-sepn. step, is used. (A) is used in at least 5:1 excess, and is particularly CFCl3; CFCl2.CF2Cl or CF2Cl.CF2Cl. The microcapsules are made of poly-L-lactide; poly-D,L-lactide or a copolymer of D,L-lactide and glycolide. USE/ADVANTAGE - The microcapsules are prepd. without formation of aggregates and in a more stable form, particularly with respect to hydrolysis. Their non-solvent content is very low (only about 1/10 that when using heptane as non-solvent) and low processing temps. are not necessary. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6183781-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9789064-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0400522-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0400522-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9742940-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-406225-B |
| priorityDate | 1985-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.