| abstract |
The use of amides of formula (I) and their pharmaceutically acceptable acid addn. salts as therapeutic agents is new, where R = (1) to (8). At least 2 of R1-R4 are H, the other two are H, halo, NO2, NH2, OH, lower alkyl, alkoxy or opt. substd. PhO or PhCH2O; R5-R7 = H or halo; R8-R10 = H, halo or lower alkyl but not all H; R11=R13 = H or halo, but not all H; R14-R19 = H, halo or lower alkyl, but R17 is not alkyl; R20 and R21 = H or lower alkyl. All (I) are new cpds. except where R = unsubstd. 2-pyridyl. Specifically claimed are 11 cpds. including N-(2-amino ethyl)-4-methoxy pyridine-2-carboxamide. |