abstract |
The compounds of the formula I, which can be used as medicaments in the form of the bases, the acid addition salts and the quaternary ammonium salts, are obtained by reacting corresponding pyrroline bases, which are substituted in the 2 position by methoxy or ethoxy, or pyrrolidone bases, which are acetalised in the 1 position, with a guanidine of the formula H2N-C(NR)-N(R4R5) in the presence of an anhydrous organic solvent. The bases which are obtained can be converted into acid addition salts, or quaternised. The meanings of the formula symbols are explained in patent claim 1. <IMAGE> |