http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-624681-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-78 |
| filingDate | 1976-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d793c1c727a8be47d509ec7763d527a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f005a9e35a41e09963fb8965d6d9ebd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f34fa1a8a32c22a590d6fa68febb2382 |
| publicationDate | 1981-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-624681-A5 |
| titleOfInvention | Process for the preparation of pyridinecarboxamides with basic substituents |
| abstract | Pyridinecarboxamides with basic substituents correspond to the general formula I <IMAGE> in which R1 is lower alkyl and -OR1 is adjacent to the carboxamide group, R2 is lower alkyl or an ethylene radical which is bonded to the trivalent radical called A and the nitrogen atom located between them to form a 6-membered ring, if R2 is lower alkyl then A is a divalent saturated hydrocarbon radical which includes not more than a single ring with 5 or 6 ring members and which has not more than 7 carbon atoms and whose two bonding points are separated by (3-m) to 4 carbon atoms, or if R2 is an ethylene radical then A is the trivalent 1-propanyl-3-ylidene radical when m is 1 or the trivalent 1,2,4-butanetriyl radical when m is zero, and one of the factors m and n is zero and the other is 1, and the ring B is further substituted if desired, and are prepared by reaction of corresponding pyridine carboxamides which have basic substituents and which have in place of the substituent OR1 a halogen atom with atomic number 17 or above or the hydroxyl group with its metal compounds of lower alkanols or with agents introducing a lower alkyl group and, if desired, subsequent salt formation. The compounds show, in particular, apomorphine- and amphetamine-antagonistic effects and can be used, in particular, as antiemetics, psychosomatics and antipsychotics. |
| priorityDate | 1976-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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