| abstract |
Aroylphenylnaphthalenes of the formula I <IMAGE> in which R is hydrogen or C1-C5-alkoxy and R1 is hydrogen or C1-C5-alkoxy, and the pharmaceutically acceptable non-toxic acid addition salts thereof are obtained by reacting a substituted tetralone with a phenylmagnesium bromide and converting resulting compounds of the formula I where appropriate into the pharmaceutically acceptable non-toxic acid addition salts. The compounds of the formula (I) which can be prepared according to the invention are, as a rule, valuable medicines. They are usually distinguished in particular by a fertility-inhibiting action and are therefore particularly suitable as fertility-inhibiting agents with oral activity in birds and mammals. The compounds of the formula (I) which can be prepared according to the invention may therefore be suitable for controlling the animal population and as contraceptives for life forms. Furthermore, these compounds can also be used, for example, for controlling animal pests. |