| abstract |
The preparation of compounds of the formula: <IMAGE> in which R represents the methyl, ethyl or n-propyl radical, is described. The process is based on the cyclisation of a mono- or diamide of beta -phthalimidoglutaric acid bearing the radical R. The compounds, in particular those in which R represents the n-propyl radical, are able to suppress the growth of tumours and have a low toxicity. |