| abstract |
The compounds of formula: <IMAGE> in which R1 and R2 represent hydrogen, a halogen, a C1-C5 alkoxy and a benzyloxy and R1 can additionally represent a hydroxyl, are obtained by reaction of a 5-(R1)tryptamine with a 5-(R2)-3-indolepyruvic acid followed by a decarboxylation of the intermediate product formed. These compounds and their salts with acids have tranquillising properties and can be used in the treatment of anxiety, irritability, sleep disorders and migraines. |