http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-601288-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-38 |
| filingDate | 1976-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45b56afe0b0884a169345456374014db |
| publicationDate | 1978-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-601288-A5 |
| titleOfInvention | 11-Piperazino-5H-di:benzodiazepine derivs. |
| abstract | Prodn. of new diazepine derivs. of formula (I) comprises reacting the ketones (II) with a metal-amine complex (in which the metal is of Gp. 4B or V), and a piperazine of formula (III) (where R1 is H, is not >4C alkyl or hydroxyalkyl, or is not >5C alkoxyalkyl. R2 is is not >4C alkyl or hydroxyalkyl, 2-4C alkenyl or is not >5C alkoxyalkyl).(I) are neuroleptics useful for treating psychotic disorders at a daily dose of 3-50 mg/kg. compared with commercial neuroleptics they have fewer side effects e.g. reduced circulatory activity. They also have antidepressant activity at 0.07-5 mg/kg per day.In an example 8-F-5-CH3-11-(4-CH3-piperazino)-5H-dibenzo b,e 1,4 diazepine was prepd. from (II; R2 is CH3) and (III; R1 is CH3). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005063254-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7491715-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7622461-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9110661-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005063254-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7550454-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7517871-B2 |
| priorityDate | 1976-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.