http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-589651-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bba0a34651fd8cd73cf83e6a9effe12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1973-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-589651-A5 |
| titleOfInvention | Pyrido (2,3-d) pyrimidine-(2,4) (1H, 3-H)-diones - antiinflammatories, analgesics and CNS depressants |
| abstract | Title cpds. of formula (I):- (where R1 is aryl, aralkyl, or cyclohexyl; and R2 is H, opt. substd. alkyl (opt. unsatd) or alkoxycarbonyl) have anti-inflammatory, analgesic, antiulcer antipyrtic, antihistaminic and CNS depressant activity. Cpds. (I; R2 = H) can be prepd. by reacting (I; R2 = H) with R'2X1 (R'2 is as R2 but not H; X1 = halogen or arylsulphonyloxy), X2CH2R3 (X2 = halogen; R3 = H or lower alkyl, R4 = CONH2, CN or alkoxycarbonyl), (R5O)2X3 (R5 is opt. substd. opt. unsatd. alkyl; X3 is CO, SO2 or COCO), CH2(X4)CH-R6 (X4 = O, OCOO or OSOO; R6 is H, lower alkyl, lower haloalkyl or aryl), or R7N2 (R7 = lower alkyl). (I; R2 = H) can be prepd. e.g. by reacting 2-aminonicotinamide with diethylcarbonate in the presence of NaOMe. |
| priorityDate | 1972-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.