| abstract |
Medicaments contain cpds. of formula (I) (where R1 is 1-10C alkyl, 3-8C cycloalkyl or phenyl and R2 is H or 1-4C alkyl) or corresponding acids of formula (II) or salts of (II). (I) and (II) in which R2 is other than CH2 when R1 is H, e.g. 6-cyclohexyl-2,3-dihydrobenzofuran-2-one and 4'-cyclopentyl-2'-hydroxyphenyl-acetic acid, are new and claimed cpds. (I) and (II) are anti-oedema, anti-inflammatory, antipyretic and analgesic agents. Daily dosage for large mammals is 20-1000 mg. Specif. claimed are cpds. (I; R1 = cyclohexyl, R2 = H), (I; R1 = cyclohexyl, R2 = CH3), and (II; R1 = cyclopentyl, R1 = H). |