http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-583255-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0016 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1970-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-583255-A5 |
| titleOfInvention | Cardenolides and bufadienolides from oxime mixtures and 3-substitution - reaction - having inotropic activity with short latent time and short |
| abstract | Cpds. of general formula (I) : (where A = groups A1-4 : R1 is H, hydroxy or acetoxy; R2 is hydroxy or acetoxy; R3 is prim., sec. or tert. amine, 2-oxo-3-oxazolidinyl or ureido; R4 is methyl or, when A = A1 where R1 = H, also hydroxymethyl, formyl or carb oxy; R5 (when R4 = hydroxymethyl, formyl or carboxy) = beta-hydroxy or beta-H, unless R4 = methyl and A = A1 with R1 = H, when R5 = alpha or beta-H) and their salts are prepd. from cpds. of formula (II) : (where X = (a) hydroxyimino or azido; (b) NH2; (c) Br or tosyloxy; (d) hydroxyethylamino); by (a) reducing to the amino gp.; (b) acylating, methylating, hydroxyethylating or carbamoylating the maino gp.; (c) reacting with a prim. or sec. amine, or (d) cyclisation to oxazolidinone. Prefd. cpds. (I) have substituents in posn. 3 in the beta-configuration. |
| priorityDate | 1970-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.