http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-579566-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D457-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-06 |
| filingDate | 1972-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-579566-A5 |
| titleOfInvention | 5-(1-alkyllysergyl)amino pyridines prodn - by alkylating 1-unsubstd. cpds., useful as salidiuretics and serotonin antagonists |
| abstract | Process for preparing new lysergic acid derivs. of formula (I) and their acid addn. salts, comprises reacting N-unsubstd. cpds. (II) with alkyl halides in presence of a strong base and in an inert solvent or solvent mixt. then opt. converting to a salt. (R=1-4C alkyl; R1 and R2=H or 1-4C alkyl). (I) are salidiuretics useful in treatment of all types of oedema and do not increase K excretion. They are generally given at 0.01-0.3 mg/kg. At 0.5-1 mg/kg they also have serotonin-antagonising activity so can be used for treating migraine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5441961-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5739146-A |
| priorityDate | 1972-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.