http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-572909-A5
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_049564710b730d1d25ef3f2c20c2e5ac |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
filingDate | 1972-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-572909-A5 |
titleOfInvention | Pyrryl-aminoethanols - prepd by redn of arylalkyl- pyrrylglyoxylamides with metal-hydrides |
abstract | Cpds. of formula (I): (where R = arylalkyl); R1 and R2 are same or different opt. branched 1-4C alkyl)are prepd. by reacting an 1-arylalkylpyrrole with an oxalylhalide and acid-binding agent to give the 1-arylalkyl-2-pyrrylglyoxyhalide which is reacted with NHR1R2 or its acid-addition salt in the presence of acid-binding agent to give a cpd. (II): This is reacted with a metal- or organometal hydride pref. sodium-bis-(2-methoxyethoxy)-aluminiumhydride in inert solvent at room temp. - boiling point of solvent. Cpds. (I) esp. known 1- 1'-(o-chlorobenzyl)-2'-pyrryl -2-di-sec. butylaminoethanol (Virimolo) have analgesic act. |
priorityDate | 1971-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.