http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-568992-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d629f98a51b15993f56f9e04fdea237f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-16 |
| filingDate | 1971-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-568992-A5 |
| titleOfInvention | 1-polyfluoroalkyl-benzodiazepines and prepn |
| abstract | 1-Polyfluoroalkyl-benzodiazepines. New cpds. (I) and their N-oxides useful as anti-anxiety, anticonvulsive sedative, hypnotic, and muscle relaxing agents (wher e R is polyfluoroalkyl; X is Hal, CF3 or NO2; Y is H, Hal, CF3, NO2, OH, 1-6 C alkyl or -alkoxy) are prepd. by standard methods for forming benzodiazepines viz, ring closure, introduction of X = Hal from X = H or NH2, isomerisation of 4,5-dihydro cpd., conversion of a tetrahydrobenzodiazepine to a 2,3-dihydro cpd. and substn. of the 5-position. 4-X-N(R)-anilines are also converted to the intermediates N-(4-X-phenyl)-ethylene diamines by reaction with ethyleneimine then the diamines are acylated with a Y.C6H4COOH deriv. |
| priorityDate | 1971-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.