http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-567509-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1972-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-567509-A5 |
| titleOfInvention | Diazepin derivs - prepd from triazolobenzodiazepinones and phenylmagnesiumhalide are central depressants, tranquillisers and |
| abstract | Cpds. of formula (I): (where R1 = H or 1-3C alkyl; A = 1-3C alkylene; R2 = OH, 1-6C alkoxy, mono- or di-arylmethoxy, dialkylamino, N-alkyl-aralkylamino or diaralkylamino (1-6C alkyl, 7-9c aralkyl), polymethyleneimino (5-7 membered) or morpholino; the cyclic residues are opts. substd. with lower alkyl and contain is not >10C including substnts.; or -AR2 forms di-(1-4C)-alkoxymethyl or (3-6C)-alkylenedioxymethyl; ring B and C are opt. substd. with F or Cl, CF3, alkyl or alkoxy with 1-6C. Acid-addn. salts of (I) are includes. Prepn. is by reacting a cpd. (II): (where R2 is not OH) or its metal derivs. with a cpd. (III): (hal = Br or I) which is dissolved in an ether and react-with (II) in inert solvent at 20-100 degrees C. Cpds. (I) are central depressants, e.g., anticonvulsants and antiaggressive aggnts. They also inhibit somatic reflexes. |
| priorityDate | 1972-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 207.