abstract |
Benzodiazepine derivs. (I) are prepd. by the method given under 'Prepn'. R1=H, 1-3C alkyl, 4-7C cycloalkylmethyl R2=H, halogen (B) Intermediates of formulae shown below:- R3=H, 1-4C alkyl, CH2Ph; R4=1-4C alkyl; R5=1 -4C alkyl, CH2Ph X=halogen; W=O, S; Y=H, OH. (I) are known as tranquillising, muscle-relaxant, anticonvulsant and hypnotic agents. |