abstract |
(A) Cpds. of general formula (I) R1=H or (1-7C) alkyl R2=H or an aliphatic or cycloaliphatic residue, e.g. (1-7C) alkyl, (2-7C) alkenyl, (3-7C) cycloalkyl, (3-7C) cycloalkenyl, (3-7C) cycloalkyl (1-4C) alkyl, or (3-7C) cycloalkenyl (1-4C) alkyl Ph1=phenylene opt. subst. e.g. by 1 or 2 alkyl, OH, ester, ether, SH, thioether, hal, CF3, NO2, NH2, Nalkyl2, NHacyl, CO2H, CONH2, CN, CO2alkyl, SO3H, SO2 alkyl, SO2NH2, and/or SO2N alkyl2 residues. and A=alkylene, alkenylene, aza alkylene, oxa alkylene or thia-alkylene residues, with at least 2C atoms separating the heteroatoms. (B) Salts of (I). (C) Functional derivs. of I, e.g. esters, amides, thioamides, nitriles, N-oxides. Anti-inflammatories. |