| abstract |
(A) Prepn. of 1,4-benzodiazepine 4-oxides (I): - R1,R2 = 1-7C alkyl or together form alkylene, aza-alkylene, N-alkylaza-alkylene, oxa-alkylene or thia-alkylene. - R3-R5 = H, halogen, 1-7C alkyl or alkoxy, CN, CF3 or NO2. - R6,R7 = H or 1-7C alkyl - R10 = 1-7C alkyl or aralkyl - (B) Cpds. (II), salts thereof, and corr. bases and their acid-addn. salts. - New route to (I); (II) have cardioactive and antibacterial props. |