http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-551949-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23J1-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23J1-00 |
filingDate | 1972-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1974-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-551949-A |
titleOfInvention | PROCESS FOR THE PREPARATION OF POLYPEPTIDES. |
abstract | Polypeptides of formula NH2-1Ala-X-Leu-Glu-Pro-6Y-Tyr-Pro-Gly-Asp-Asp-12Ala-13Thr-Pro-Z-G- ln-Met-18Ala-Gln-Tyr-Ala-Ala-Z'-24Leu-25Arg-Arg-Tyr-Ile-Asn-30Met- -Leu-Thr-Arg-Pro-Arg-36Tyr-C-NH2 (I) where the nomenclature follows JACS, 67, 1524, 1530, and where in different proteins e.g. bovine, X is Pro, Y is Gln, Z and Z' are Glu, porcine X is Pro, Y is Val, Z and Z' are Glu, are prepd. by emulsifying pancreatic gland in a water-immiscible solvent, adding aq. alcohol acidified to pH 2.8, filtering off insol. tissue, adding alkali hydroxide to pH 8-8.5 and sepng. fatty material and ammonium phosphate, acidifying to pH 5.2, diluting with diethyl ether and ethanol standing for is not 12 hours, and recovering the polypeptides (I). (I) increases intestinal mobility, constricts the hepatic duct and loosens th bile vesicle. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5202421-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0376251-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0376251-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5300490-A |
priorityDate | 1972-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.