abstract |
Cpds. (I) (where A is 1-3C alkylene and R1 is 3-18C aliphatic hydrocarbyl) are prepd. by methods where the ester group is formed on a piperazinyl dibenzoxepine deriv. This (I, A = CH2CH2 R-hexyl) is prepd. by esterifying 2-trifluoromethylsulphonyl-11-(4-beta-hydroxyethyl-1-piperazinyl) dibenzo b,f 1,4 oxazepine with heptanoyl chloride. |