http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-546225-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-275 |
| filingDate | 1970-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0f7030c9be2ad3bdf435fc5a86d8c84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc0dddcfb2bd0aca09dbce260057b122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_305d2aa5b8afdc32daf8873cd554bf50 |
| publicationDate | 1974-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-546225-A |
| titleOfInvention | PROCESS FOR THE PREPARATION OF 1- (2-NITRILPHENOXY) -2-HYDROXY-3-AETHYLAMINOPROPANE AND ITS SALTS. |
| abstract | The title cpd. and its optical isomers and acid addn. salts have beta-adrenolytic activity and may be used for treatment or prophylaxis of heart diseases and arrythmia, esp. tachycardia. They may be prepd. (a) by reacting a cpd. (II): (where Z = or CHOH-CH2Hal) with N,N'-diethyl-urea, (b) reacting (II) with ethylamine, (c) reacting 3-(o-cyanophenoxy)-2-hydroxypropylamine with a cpd. C2H5X (where is a labile anionic gp). (d) replacing the protecting gp. of the corresp. protected -OH cpd. by H, (e) hydrolysing 3-ethyl-5-(2-cyanophenoxymethyl)-oxazolidinone-(2), (f) hydrolysing or pyrolysing the corresp. urea deriv. (g) splitting off the protecting gp. from the corresp. N-protected cpd. (h) converting a ring substituent into a cyano gp. |
| priorityDate | 1969-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.