http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-545783-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
filingDate | 1971-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1974-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-545783-A |
titleOfInvention | Novel indole derivs - prepn by reacting 4-(2-hydroxy-3-isopropylaminopropoxy) indoles and acid anhy-drides |
abstract | Derivatives of formula (I) (where R2 and R3 are H, or CH3, and either (a) R1 is 1,1-dimethyl-2-propynyl or allyl and R4 is cycloalkyl opt. mono- or polysubstd. by lower alkyl, phenyl opt. substd. by CH3, OCH3, F and/or Cl, chloroalkyl or alkyl, or (b) R1 is lower alkyl, 3-6C cycloalkyl or phenylalkyl and R4 is chloroalkyl or phenyl opt. substd. by CH3, OCH3, F and/or Cl) and their acid addn. salts, which have beta-adrenergic receptor blocking and antiarrhythmic activity and can be used for the treatment and prophylaxis of coronary diseases and for the treatment of disturbances in heart rhythm, are prepd. by reacting cpds. of formula (I; OCOR4 is OH) with anhydrides of (R4CO)2O in the presence of R4COOH. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5223073-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DK-152120-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S568834-B2 |
priorityDate | 1971-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.