http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-537946-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 |
filingDate | 1970-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab5fdd4e016e9d94aab0cab8cc618a11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7384b728968843451657d1da274fbb99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_962b1fd1560e6cac21b599c1fb06b276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d14ab9cf415cb10939bf257495500a5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7afb7fa9cdf5f1664d026cad4b198d87 |
publicationDate | 1973-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-537946-A |
titleOfInvention | Process for the preparation of new derivatives of 7-aminocephalosporanic acid |
abstract | Therapeutically active cpds. (I) (where R1 is an esp. p- or m- opt. lower alkyl-substd. aminopyridinium gp. and R2 is H or a free or carboxylic acid-esterified OH gp., in which the ester-O atoms may be substd. by S, or an opt. N-substd. carbamoyloxy gp., e.g. -O-CO-NHR3 where R3 is esp. lower alkyl opt. substd. by one or more Cl atoms, or a thiocarbamoylmercapto gp) are prepd. by acylating cpds. (II) with the R1CH2CO gp. (I) have anti-bacterial activity against gram +ve and -ve bacteria, e.g. penicillin-resistant Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Salmonella typhosa and are useful in pharmaceutical compsns, food additives, food preservatives and disinfectants. Pref. (I) where R2 is acetoxy are converted to OH-cpds. which may be reacted with an isocyanate ester to form (I) where R2 is an N-substd. carbamoyloxy gp. |
priorityDate | 1970-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.