| abstract |
or 4-pyridyl)- isoquinolines. Of the formula (I):- (where R1 and R2 = same or different 1-4C alkyl and R3=H, 1 to 4C alkyl or halogen) are prepared by reacting alkyl benzenes. of the formula (II):- (where R'1 = H or lower alkyl (R1 = CH2R'1) with 3- or 4-cyanopyridine or its acid addition salts at 50-180 degrees C in the presence of an acid condensing agent. The products have antiphlogistic, antipyretic, analgesic, spasmolytic and sedative activity. |