http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-535232-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-327 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-327 |
| filingDate | 1967-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_648934ca7818a9c1186ddf388032a877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b492400233f1f252888d7b41a2cc254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171991419974e380b0b0ed55782abe97 |
| publicationDate | 1973-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-535232-A |
| titleOfInvention | Process for the production of new, substituted phenylacetic acids and their esters |
| abstract | (A) Substituted phenylacetic acids and -esters (I): R1 = H, alkyl, alkenyl or alkinyl; R2 = H, alkyl, alkoxy or halogen; R3, R4 and R5 are H or alkyl. (B) Salts of (I) with inorganic and organic bases. Compounds (I) have analgesic-, antiphlogistic- and antipyretic activity with very favourable therapeutic index. They may be used to alleviate or remove pain as well as in the treatment of rheumatic- and other inflammatory processes. 0.20 mol of (p-aminophenyl) acetic acid (Radiszewski, Ber. 2, 209; Bedson, J.Chem. Soc 37, 92) and 0.20 mol of 2.5- dimethoxytetrahydrofuran are refluxed in 40 ml glacial acetic acid for 30 minutes. After cooling the mixture is poured into 160 ml. water, the crystals filtered off, washed with water and dried for 15 hours at 70 deg.C. The brown powder obtained is extracted with benzene. Evaporation of the extract gives the (p-(1-pyrryl) phenyl) acetic acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4618612-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0177659-A1 |
| priorityDate | 1966-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.